Octopus
4 April 2023 The first patients have been recruited for a revolutionary trial, led by UCL researchers, that will transform the way that treatments are tested for progressive multiple sclerosis (MS). Octopus is a world-first clinical trial, funded by the MS Society and led by researchers at the MRC Clinical Trials Unit at UCL.
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The Octopus trial is intended to accelerate the search for drugs to treat progressive MS by comparing three against the same control group and rolling trial phases together. The design.
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Octopus is a revolutionary trial that will transform the way we test treatments for progressive MS. A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster.
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Inside the MS Octopus mega-trial: inspired by cancer, supported by patients Features Inside the MS mega-trial: inspired by cancer, supported by patients The UK MS Society discusses how it plans to research treatments for progressive MS. Kezia Parkins June 23, 2021
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Octopus is a revolutionary trial that will transform the way we test treatments for progressive MS. A smarter way of testing potential treatments, it could deliver life-changing new treatments up to three times faster. The trial team have now confirmed the first treatments they'll be testing .
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Octopus will test several experimental MS therapies against a shared control group. Treatments that appear effective from early data can continue into the next stage without needing to set up a.
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Octopus is a clinical trial evaluating several potential treatments for primary and secondary progressive multiple sclerosis (MS).
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Introducing Octopus - the world's first multi-arm, multi-stage trial for MS Tuesday 4 May 2021 We're pleased to introduce Octopus - our revolutionary, multi-arm, multi-stage trial that will transform the way we test treatments for progressive MS.
'Major moment in MS research' as new Octopus trial starts Lounge
Octopus is the first multi-arm, multi-stage (MAMS) trial for MS. It's designed to transform the way treatments for progressive MS are tested. And it's being led by researchers at University College London. Octopus is currently testing two drugs already used in other conditions. University College London Hospital is currently the only site open.
This octopus learned to use a camera faster than some humans The Independent The Independent
This is a real unmet need for people living with MS, many of whom have no treatments to slow disability progression at the moment. The Octopus trial is designed to slot in new drugs asthey're discovered. We hope that Octopus will test more drugs - or combinations of drugs - that can stop progression of the disease altogether, and even one.
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Launched in April 2023, Octopus is a revolutionary MS clinical trial that will transform the way we test treatments for progressive MS. The trial is devised to be smarter than the current standard style of clinical trial.
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A broad-reaching trial of already-approved drugs is hoped to turn up new treatment options for people with progressive forms of MS. Octopus Study to Test Drug Effects on Progressive MS
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Octopus is a trial which will test multiple treatments with the aim to find one that can slow down, and ultimately stop, the progression of disability in people with primary or secondary progressive MS. Octopus aims to be a more efficient kind of clinical trial by using the multi-arm, multi-stage (MAMS) approach, visit this page about MAMS for.
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Jeremy Chataway, MA, PhD, FRCP, UCL Institute of Neurology, London, UK, gives an insight into the Octopus trial, the first-ever multi-arm, multi-stage (MAMS).
Octopus trial one step closer to launch MS Society
The Octopus MS clinical trial is the first multi-arm, multi-stage trial for MS. The trial is led by researchers at University College London and is currently testing two drugs already used in other conditions against a placebo (dummy drug). These are metformin and alpha lipoic acid.
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OCTOPUS is the first MS trial to use a type of trial design known as multi-arm multi-stage (MAMS). This method can have many advantages over traditional trials: It allows several treatments to be tested at the same time against a common control (i.e. "multi-arm"). Treatments which appear to be effective from the early data can continue onto.